How Immunogenic is your Product?

The develpoment of modern pharmaceuticals, cosmetics and food implies the availability of sensitive tests to analyse the immunogenicity of individual components. On the other side more and more vaccines are developed to stimulate the immune system for treatment of a broad spectrum of diseases.

Are you looking for outsourcing opportunities to charaterize your product immunologically?

GLYCOTOPE offers a broad range of services in state-of-the-art techniques to test or optimize cellular and humoral responses in vitro and in vivo.

Use our extensive experience in immunology, molecular biology and cell biology based on a vast range of different techniques in the areas of dendritic cell, T-cell, macrophage, NK cell, and NKT cell biology.
We offer customized solutions for the individual requirements of your project.


How does your Product affect the Immune System?
We evaluate its immunomodulating potential using mouse models, DNA Arrays or different cellular assays: DC differentiation, maturation and antigen presentation, activation and functional modulation of T cells, NK cells or macrophages, effects on vitality, apoptosis and proliferation.
We identify, validate and optimize T cell epitopes of your drug e.g. by ELISPOT analysis.

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Test the Potency of your Vaccine?

We analyze and optimize the potency of your vaccine in mouse models determining humoral (antibody titres, isotypes, specificities) and cellular
(DTH, antigen-specific T-cells) responses.

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Do you need Support in Immunomonitoring or Product Development?

Use our experience and well established techniques: ELISPOT analysis, T- and DC cytokine profiling, Tetramer staining, T-cell cloning, analysis for CTL activity and humoral responses (antibody titres, isotypes, specificities).

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Quality control is essentially connected with well defined standards which are difficult to obtain for cellular assays. We have the solution for all assays where dendritic cells are involved!

Do you need a Standard for Quality Control?

Use our well characterized dendritic cell line NemodDC and T cell products offering the unique possibility of standardization e.g. for flow cytometry, DC differentiation and maturation, T cell activation & cloning or antigen processing and presentation.

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Company Contact

GLYCOTOPE GmbH
Robert-Rössle-Str. 10
13125 Berlin
Germany

Hans Baumeister, Ph.D.
Chief Operating Officer
Telephone:  
Fax:
E-mail:
 +49-30-941084-207
+49-30-941084-188
hans.baumeister@glycotope.com