Cell Line Development

punkteFor the development of therapeutic proteins, the choice of an appropriate cell line is crucial, in particular due to the distinct glycosylation patterns of available cell lines and – apart from a strong influence on the product´s characeristics – their potential immunogenicity.

Glycotope has a long track record in developing serum-free cell lines for the production of biotherapeutics with focus on glycoproteins. The following solutions have proven to offer excellent results:


  • GlycoProfiling of mammalian cell lines or clones before or early after transfection to identify a suitable glycosylation pattern
  • GlycoExpress™, our proprietary human expression and production system to achieve a fully human glycosylation tailored to your needs

We use the automated ClonePixFL for identifying and cloning high yield expression clones.

Print