The development of biotherapeutics, especially vaccines and immunotherapeutics, requires the sophisticated assessment of immune responses in human clinical trials. Immune cell-mediated modes of action became more and more important for biotherapeutics and involve the activity of specialized cells including macrophages, dendritic cells, natural killer cells (NK), antigen-specific cytotoxic T lymphocytes, helper T lymphocytes and the release of various cytokines in response to an antigen stimulation. Finally, genetic mutations can affect the efficacy of drugs. Glycotope Biotechnology provides its customers full project consultancy, including assay creation and validation, sample measurement and immune monitoring in clinical trials.Based on a variety of technology platforms and measurements, Glycotope provides comprehensive services for immunogenicity testing, pharmacokinetic (PK) and pharmacodynamics (PD) assessment measures.

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